Role of microRNA-150 in solid tumors

The role of Src in solid tumors.

The proto-oncogene c-Src (Src) encodes a nonreceptor tyrosine kinase whose expression and activity are correlated with advanced malignancy and poor prognosis in a variety of human cancers. Nine additional enzymes with homology to Src have been identified and collectively are referred to as Src family kinases (SFKs). Together, SFKs represent the largest family of nonreceptor tyrosine kinases and...

role of cultural iran in promotion of multilaieralism in central asia and caucasus

cultural iran is a scope that is more extended than the political territories of iran as a political unit. this concept means that cultural geography(mehdi moghanlo-1383-1) of iran is greater than its political geography which, according to history, has a long history extending west-east from kandahar to the euphrates and north-south from the persian gulf to the caucasus including transoxiana a...

Solid tumors of childhood display specific serum microRNA profiles.

BACKGROUND Serum biomarkers for diagnosis and risk stratification of childhood solid tumors would improve the accuracy/timeliness of diagnosis and reduce the need for invasive biopsies. We hypothesized that differential expression and/or release of microRNAs (miRNAs) by such tumors may be detected as altered serum miRNA profiles. METHODS We undertook global quantitative reverse transcription ...

MicroRNA miR-150 Is Involved in V

Serum microRNAs in childhood tumors 1 Solid tumors of childhood display specific serum microRNA profiles

1 Solid tumors of childhood display specific serum microRNA profiles Matthew J. Murray, Katie L. Raby, Harpreet K. Saini, Shivani Bailey, Sophie V. Wool, Jane M. Tunnacliffe, Anton J. Enright, James C. Nicholson, Nicholas Coleman. 1 Department of Paediatric Haematology and Oncology, Addenbrooke’s Hospital, Hills Road, Cambridge, CB2 0QQ, UK 2 Department of Pathology, University of Cambridge, Te...